When a customer cashes their own personal check for "cash" instead of using a bank withdrawal slip, is a CTR completed with the "Deposit / Withdrawal" box checked or the "Negotiable Instruments Cashed" box checked?

FinCEN says unofficially that it would prefer you check "negotiable instruments cashed" in such cases. Apparently law enforcement prefers that method.

What about the customer who uses a DDA debit to withdraw the funds- withdrawal or negotiable instrument cashed?

If the individual uses an internal form that is not negotiable, use "withdrawal."