I'm not sure why you would accept a wire without the name of the beneficiary? I guess that's a different thread though. You can check the Travel Rule on what is required for funds transfers.
Regarding OFAC - if ABC is your customer and ABC is the beneficiary of the wire and you're screening your customer base against the SDN List on a weekly basis I think the odds that the beneficiary of the wire being a sanctioned party is slim. The risk is there, but it's minimal.
"100 victories in 100 battles isnt the most skillful. Subduing the other's military w/o battle is the most skillful." Sun-Tzu