If a business has a loan secured by personal real estate as collateral instead of business real estate, would the bank be required to send a 1098 and report the interest?

If a loan to an individual is secured by real estate, 1098 reporting applies. Neither the nature of the real estate nor the purpose of the loan are factors.

If the "business" is an entity; e.g. corporation, LLC, etc., 1098 reporting is not required.