Unless of course it involves a wire transfer or monetary instrument sale with a non-customer
Note the "In general..." preface. Regardless, the instructions indicate you check originators, not recipients on outgoing wires and recipients not originators on incoming wires. On official checks you check remitters not payees. In both cases it only applies to transactions subject to record retention.
If the transaction is subject to record retention, but the purchaser/originator is not a deposit account holder/established customer the bank is required to fully identify them and keep the information for 5 years. You might say they are not a "customer" within the CIP definition, but it's clear you have chosen to do business with them and have information you could provide to the party initiating the 314(a) query.
beachgirl... My resposne was to Wizard. The reference to "the mothership" was an allusion to the web site where Wizard goes to download the list.