Regulation to Help Prove Fake Signature

If a merchant provides a signed receipt on a disputed debit card charge and we know for sure it is not the customer’s signature that is disputing the charge, is there anything a Bank can do?I know Reg E is very consumer friendly but if the signature definitely does not match, the Bank will have to side with the customer and assume it was fraud and work the dispute, and take any loss associated with it. I am curious if there is anything else the Bank can do from a Regulation stand point that could help the Bank not take a loss.